The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

An open and decondensed chromatin organization is a defining property of pluripotency. Several epigenetic regulators have been implicated in maintaining an open chromatin organization, but how these processes are connected to the pluripotency network is unknown. Here, we identified a new role for th...

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Veröffentlicht in:Genes Dev
Hauptverfasser: Novo, Clara Lopes, Tang, Calvin, Ahmed, Kashif, Djuric, Ugljesa, Fussner, Eden, Mullin, Nicholas P., Morgan, Natasha P., Hayre, Jasvinder, Sienerth, Arnold R., Elderkin, Sarah, Nishinakamura, Ryuichi, Chambers, Ian, Ellis, James, Bazett-Jones, David P., Rugg-Gunn, Peter J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863740/
https://ncbi.nlm.nih.gov/pubmed/27125671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.275685.115
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