The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

An open and decondensed chromatin organization is a defining property of pluripotency. Several epigenetic regulators have been implicated in maintaining an open chromatin organization, but how these processes are connected to the pluripotency network is unknown. Here, we identified a new role for th...

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Bibliografiska uppgifter
I publikationen:Genes Dev
Huvudupphovsmän: Novo, Clara Lopes, Tang, Calvin, Ahmed, Kashif, Djuric, Ugljesa, Fussner, Eden, Mullin, Nicholas P., Morgan, Natasha P., Hayre, Jasvinder, Sienerth, Arnold R., Elderkin, Sarah, Nishinakamura, Ryuichi, Chambers, Ian, Ellis, James, Bazett-Jones, David P., Rugg-Gunn, Peter J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863740/
https://ncbi.nlm.nih.gov/pubmed/27125671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.275685.115
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