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Global Chromatin Architecture Reflects Pluripotency and Lineage Commitment in the Early Mouse Embryo

An open chromatin architecture devoid of compact chromatin is thought to be associated with pluripotency in embryonic stem cells. Establishing this distinct epigenetic state may also be required for somatic cell reprogramming. However, there has been little direct examination of global structural do...

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Detalhes bibliográficos
Main Authors: Ahmed, Kashif, Dehghani, Hesam, Rugg-Gunn, Peter, Fussner, Eden, Rossant, Janet, Bazett-Jones, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866533/
https://ncbi.nlm.nih.gov/pubmed/20479880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010531
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