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Global Chromatin Architecture Reflects Pluripotency and Lineage Commitment in the Early Mouse Embryo

An open chromatin architecture devoid of compact chromatin is thought to be associated with pluripotency in embryonic stem cells. Establishing this distinct epigenetic state may also be required for somatic cell reprogramming. However, there has been little direct examination of global structural do...

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Autors principals: Ahmed, Kashif, Dehghani, Hesam, Rugg-Gunn, Peter, Fussner, Eden, Rossant, Janet, Bazett-Jones, David P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866533/
https://ncbi.nlm.nih.gov/pubmed/20479880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010531
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