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Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres

The mammalian genome is compacted to fit within the confines of the cell nucleus. DNA is wrapped around nucleosomes, forming the classic ‘beads-on-a-string’ 10-nm chromatin fibre. Ten-nanometre chromatin fibres are thought to condense into 30-nm fibres. This structural reorganization is widely assum...

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Autors principals: Fussner, Eden, Strauss, Mike, Djuric, Ugljesa, Li, Ren, Ahmed, Kashif, Hart, Michael, Ellis, James, Bazett-Jones, David P
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492707/
https://ncbi.nlm.nih.gov/pubmed/22986547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.139
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