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Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres
The mammalian genome is compacted to fit within the confines of the cell nucleus. DNA is wrapped around nucleosomes, forming the classic ‘beads-on-a-string’ 10-nm chromatin fibre. Ten-nanometre chromatin fibres are thought to condense into 30-nm fibres. This structural reorganization is widely assum...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
European Molecular Biology Organization
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492707/ https://ncbi.nlm.nih.gov/pubmed/22986547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.139 |
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