The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells

An open and decondensed chromatin organization is a defining property of pluripotency. Several epigenetic regulators have been implicated in maintaining an open chromatin organization, but how these processes are connected to the pluripotency network is unknown. Here, we identified a new role for th...

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Vydáno v:Genes Dev
Hlavní autoři: Novo, Clara Lopes, Tang, Calvin, Ahmed, Kashif, Djuric, Ugljesa, Fussner, Eden, Mullin, Nicholas P., Morgan, Natasha P., Hayre, Jasvinder, Sienerth, Arnold R., Elderkin, Sarah, Nishinakamura, Ryuichi, Chambers, Ian, Ellis, James, Bazett-Jones, David P., Rugg-Gunn, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4863740/
https://ncbi.nlm.nih.gov/pubmed/27125671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.275685.115
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