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A scalable method for the production of high-titer and high-quality adeno-associated type 9 vectors using the HSV platform
Recombinant adeno-associated vectors based on serotype 9 (rAAV9) have demonstrated highly effective gene transfer in multiple animal models of muscular dystrophies and other neurological indications. Current limitations in vector production and purification have hampered widespread implementation of...
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| Udgivet i: | Mol Ther Methods Clin Dev |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863725/ https://ncbi.nlm.nih.gov/pubmed/27222839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.31 |
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