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Sodium Chloride Enhances Recombinant Adeno-Associated Virus Production in a Serum-Free Suspension Manufacturing Platform Using the Herpes Simplex Virus System

The increase in effective treatments using recombinant adeno-associated viral (rAAV) vectors has underscored the importance of scalable, high-yield manufacturing methods. Previous work from this group reported the use of recombinant herpes simplex virus type 1 (rHSV) vectors to produce rAAV in adher...

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Vydáno v:Hum Gene Ther Methods
Hlavní autoři: Adamson-Small, Laura, Potter, Mark, Byrne, Barry J., Clément, Nathalie
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346630/
https://ncbi.nlm.nih.gov/pubmed/28117600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.151
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