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Copackaging of Multiple Adeno-Associated Viral Vectors in a Single Production Step

Limiting factors in large preclinical and clinical studies utilizing adeno-associated virus (AAV) for gene therapy are focused on the restrictive packaging capacity, the overall yields, and the versatility of the production methods for single AAV vector production. Furthermore, applications where mu...

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Pubblicato in:Hum Gene Ther Methods
Autori principali: Doerfler, Phillip A., Byrne, Barry J., Clément, Nathalie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346231/
https://ncbi.nlm.nih.gov/pubmed/25143183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.055
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