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Large-Scale Adeno-Associated Viral Vector Production Using a Herpesvirus-Based System Enables Manufacturing for Clinical Studies

The ability of recombinant adeno-associated viral (rAAV) vectors to exhibit minimal immunogenicity and little to no toxicity or inflammation while eliciting robust, multiyear gene expression in vivo are only a few of the salient features that make them ideally suited for many gene therapy applicatio...

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Detalhes bibliográficos
Main Authors: Clément, Nathalie, Knop, David R., Byrne, Barry J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861951/
https://ncbi.nlm.nih.gov/pubmed/19569968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.094
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