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The role of ciliary trafficking in Hedgehog receptor signaling
Defects in the biogenesis of or transport through primary cilia affect Hedgehog protein signaling, and many Hedgehog pathway components traffic through or accumulate in cilia. The Hedgehog receptor, Patched, negatively regulates the activity and ciliary accumulation of Smoothened, a seven transmembr...
Tallennettuna:
| Julkaisussa: | Sci Signal |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4863716/ https://ncbi.nlm.nih.gov/pubmed/26038600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa5622 |
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