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Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
Primary cilia interpret vertebrate Hedgehog (Hh) signals. Why cilia are essential for signaling is unclear. One possibility is that some forms of signaling require a distinct membrane lipid composition, found at cilia. We found that the ciliary membrane contains a particular phosphoinositide, PI(4)P...
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| Veröffentlicht in: | Dev Cell |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4557815/ https://ncbi.nlm.nih.gov/pubmed/26305592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.08.001 |
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