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Modeling the interaction between danoprevir and mericitabine in the treatment of chronic HCV infection

Modeling HCV RNA decline kinetics under therapy has proven useful for characterizing treatment effectiveness. Here we model HCV viral kinetics (VK) in 72 patients given a combination of danoprevir, a protease inhibitor and mericitabine, a nucleoside polymerase inhibitor for 14 days in the INFORM-1 t...

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Detalhes bibliográficos
Publicado no:Antivir Ther
Main Authors: Canini, Laetitia, Guedj, Jeremie, Chatterjee, Anushree, Lemenuel-Diot, Annabelle, Smith, Patrick F, Perelson, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862948/
https://ncbi.nlm.nih.gov/pubmed/26555159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP3006
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