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Mathematical modeling of HCV infection: what can it teach us in the era of direct antiviral agents?

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and affects nearly 170 million people worldwide. Whereas the previous standard of care with pegylated interferon and ribavirin had a modest effectiveness, the recent approval of two highly potent protease inhibitors and the...

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Detalhes bibliográficos
Main Authors: Chatterjee, Anushree, Guedj, Jeremie, Perelson, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641583/
https://ncbi.nlm.nih.gov/pubmed/23186606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2428
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