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Mathematical modeling of HCV infection: what can it teach us in the era of direct antiviral agents?

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and affects nearly 170 million people worldwide. Whereas the previous standard of care with pegylated interferon and ribavirin had a modest effectiveness, the recent approval of two highly potent protease inhibitors and the...

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Main Authors: Chatterjee, Anushree, Guedj, Jeremie, Perelson, Alan S.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641583/
https://ncbi.nlm.nih.gov/pubmed/23186606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2428
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