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Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128)
Mericitabine (RG7128) is a first-in class nucleoside polymerase inhibitor (NPI), which requires intracellular uptake and phosphorylation to two active triphosphates. Mathematical modeling has provided important insights for characterizing HCV-RNA decline and estimating in vivo effectiveness of antiv...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322641/ https://ncbi.nlm.nih.gov/pubmed/22095398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24788 |
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