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Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128)

Mericitabine (RG7128) is a first-in class nucleoside polymerase inhibitor (NPI), which requires intracellular uptake and phosphorylation to two active triphosphates. Mathematical modeling has provided important insights for characterizing HCV-RNA decline and estimating in vivo effectiveness of antiv...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guedj, Jeremie, Dahari, Harel, Shudo, Emi, Smith, Patrick, Perelson, Alan S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322641/
https://ncbi.nlm.nih.gov/pubmed/22095398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24788
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