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Modeling hepatitis C virus kinetics: the relationship between the infected cell loss rate and the final slope of viral decay

BACKGROUND: Patients infected with hepatitis C virus (HCV) who respond to treatment with interferon-α plus ribavirin exhibit biphasic or triphasic viral load declines. While the rapid first phase is indicative of the effectiveness of therapy in blocking viral production, ε, the slope of the final ph...

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Detalhes bibliográficos
Main Authors: Dahari, Harel, Shudo, Emi, Cotler, Scott J., Layden, Thomas J., Perelson, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874964/
https://ncbi.nlm.nih.gov/pubmed/19474480
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