Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B

Molecular, cellular, and clinical studies have combined to demonstrate a contribution from the DNA cytosine deaminase APOBEC3B (A3B) to the overall mutation load in breast, head/neck, lung, bladder, cervical, ovarian, and other cancer types. However, the complete landscape of mutations attributable...

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Udgivet i:PLoS One
Main Authors: Akre, Monica K., Starrett, Gabriel J., Quist, Jelmar S., Temiz, Nuri A., Carpenter, Michael A., Tutt, Andrew N. J., Grigoriadis, Anita, Harris, Reuben S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862684/
https://ncbi.nlm.nih.gov/pubmed/27163364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155391
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