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Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment

Gastrointestinal (GI) defects, including gastroesophageal reflux, constipation and delayed gastric emptying, are common in patients with spinal muscular atrophy (SMA). Similar GI dysmotility has been identified in mouse models with survival of motor neuron (SMN) protein deficiency. We previously des...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Sintusek, Palittiya, Catapano, Francesco, Angkathunkayul, Napat, Marrosu, Elena, Parson, Simon H., Morgan, Jennifer E., Muntoni, Francesco, Zhou, Haiyan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862622/
https://ncbi.nlm.nih.gov/pubmed/27163330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155032
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