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Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy

The identification of noninvasive biomarkers to monitor the disease progression in spinal muscular atrophy (SMA) is becoming increasingly important. MicroRNAs (miRNAs) regulate gene expression and are implicated in the pathogenesis of neuromuscular diseases, including motor neuron degeneration. In t...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Catapano, Francesco, Zaharieva, Irina, Scoto, Mariacristina, Marrosu, Elena, Morgan, Jennifer, Muntoni, Francesco, Zhou, Haiyan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014531/
https://ncbi.nlm.nih.gov/pubmed/27377135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.47
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