Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy

The identification of noninvasive biomarkers to monitor the disease progression in spinal muscular atrophy (SMA) is becoming increasingly important. MicroRNAs (miRNAs) regulate gene expression and are implicated in the pathogenesis of neuromuscular diseases, including motor neuron degeneration. In t...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Catapano, Francesco, Zaharieva, Irina, Scoto, Mariacristina, Marrosu, Elena, Morgan, Jennifer, Muntoni, Francesco, Zhou, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014531/
https://ncbi.nlm.nih.gov/pubmed/27377135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.47
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