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Histopathological Defects in Intestine in Severe Spinal Muscular Atrophy Mice Are Improved by Systemic Antisense Oligonucleotide Treatment

Gastrointestinal (GI) defects, including gastroesophageal reflux, constipation and delayed gastric emptying, are common in patients with spinal muscular atrophy (SMA). Similar GI dysmotility has been identified in mouse models with survival of motor neuron (SMN) protein deficiency. We previously des...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Sintusek, Palittiya, Catapano, Francesco, Angkathunkayul, Napat, Marrosu, Elena, Parson, Simon H., Morgan, Jennifer E., Muntoni, Francesco, Zhou, Haiyan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862622/
https://ncbi.nlm.nih.gov/pubmed/27163330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155032
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