The altered expression of neurofilament in mouse models and patients with spinal muscular atrophy

OBJECTIVES: To investigate the levels of neurofilaments (NFs) in transgenic mice and patients with spinal muscular atrophy (SMA), and to evaluate their efficacy as a biomarker in SMA. METHODS: The levels of NF mRNA transcripts were measured by quantitative real‐time PCR in spinal cord from SMA mice....

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Spicer, Charlotte, Lu, Ching‐Hua, Catapano, Francesco, Scoto, Mariacristina, Zaharieva, Irina, Malaspina, Andrea, Morgan, Jennifer E., Greensmith, Linda, Muntoni, Francesco, Zhou, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045929/
https://ncbi.nlm.nih.gov/pubmed/33683023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51336
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