Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication

Viruses are solely dependent on host cells to propagate; therefore, understanding virus-host interaction is important for antiviral drug development. Since de novo nucleotide biosynthesis is essentially required for both host cell metabolism and viral replication, specific catalytic enzymes of these...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wang, Yijin, Wang, Wenshi, Xu, Lei, Zhou, Xinying, Shokrollahi, Ehsan, Felczak, Krzysztof, van der Laan, Luc J. W., Pankiewicz, Krzysztof W., Sprengers, Dave, Raat, Nicolaas J. H., Metselaar, Herold J., Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862450/
https://ncbi.nlm.nih.gov/pubmed/26926637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02700-15
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