Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication

Norovirus is a major cause of acute gastroenteritis worldwide and has emerged as an important issue of chronic infection in transplantation patients. Since no approved antiviral is available, we evaluated the effects of different immunosuppressants and ribavirin on norovirus and explored their mecha...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Dang, Wen, Yin, Yuebang, Wang, Yijin, Wang, Wenshi, Su, Junhong, Sprengers, Dave, van der Laan, Luc J. W., Felczak, Krzysztof, Pankiewicz, Krzysztof W., Chang, Kyeong-Ok, Koopmans, Marion P. G., Metselaar, Herold J., Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655111/
https://ncbi.nlm.nih.gov/pubmed/28807916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01095-17
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