Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication

Norovirus is a major cause of acute gastroenteritis worldwide and has emerged as an important issue of chronic infection in transplantation patients. Since no approved antiviral is available, we evaluated the effects of different immunosuppressants and ribavirin on norovirus and explored their mecha...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Dang, Wen, Yin, Yuebang, Wang, Yijin, Wang, Wenshi, Su, Junhong, Sprengers, Dave, van der Laan, Luc J. W., Felczak, Krzysztof, Pankiewicz, Krzysztof W., Chang, Kyeong-Ok, Koopmans, Marion P. G., Metselaar, Herold J., Peppelenbosch, Maikel P., Pan, Qiuwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655111/
https://ncbi.nlm.nih.gov/pubmed/28807916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01095-17
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