Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication

Norovirus is a major cause of acute gastroenteritis worldwide and has emerged as an important issue of chronic infection in transplantation patients. Since no approved antiviral is available, we evaluated the effects of different immunosuppressants and ribavirin on norovirus and explored their mecha...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Dang, Wen, Yin, Yuebang, Wang, Yijin, Wang, Wenshi, Su, Junhong, Sprengers, Dave, van der Laan, Luc J. W., Felczak, Krzysztof, Pankiewicz, Krzysztof W., Chang, Kyeong-Ok, Koopmans, Marion P. G., Metselaar, Herold J., Peppelenbosch, Maikel P., Pan, Qiuwei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655111/
https://ncbi.nlm.nih.gov/pubmed/28807916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01095-17
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