Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication

Norovirus is a major cause of acute gastroenteritis worldwide and has emerged as an important issue of chronic infection in transplantation patients. Since no approved antiviral is available, we evaluated the effects of different immunosuppressants and ribavirin on norovirus and explored their mecha...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Dang, Wen, Yin, Yuebang, Wang, Yijin, Wang, Wenshi, Su, Junhong, Sprengers, Dave, van der Laan, Luc J. W., Felczak, Krzysztof, Pankiewicz, Krzysztof W., Chang, Kyeong-Ok, Koopmans, Marion P. G., Metselaar, Herold J., Peppelenbosch, Maikel P., Pan, Qiuwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655111/
https://ncbi.nlm.nih.gov/pubmed/28807916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01095-17
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