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Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity
Integrin-dependent adhesions are mechanosensitive structures in which talin mediates a linkage to actin filaments either directly or indirectly by recruiting vinculin. Here, we report the development and validation of a talin tension sensor. We find that talin in focal adhesions is under tension, wh...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4862330/ https://ncbi.nlm.nih.gov/pubmed/27161398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201510012 |
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