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Synthesis and Evaluation of Cytosolic Phospholipase A(2) Activatable Fluorophores for Cancer Imaging

Activatable fluorophores selective to cytosolic phospholipase A(2) (cPLA(2)) were synthesized and evaluated for their ability to image triple negative breast cancer cells. The activatable constructs were synthesized by esterification of a small molecule fluorophore with a fatty acid resulting in abl...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Chiorazzo, Michael G., Bloch, Noah B., Popov, Anatoliy V., Delikatny, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862311/
https://ncbi.nlm.nih.gov/pubmed/26426140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00417
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