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Synthesis and Evaluation of Cytosolic Phospholipase A(2) Activatable Fluorophores for Cancer Imaging

Activatable fluorophores selective to cytosolic phospholipase A(2) (cPLA(2)) were synthesized and evaluated for their ability to image triple negative breast cancer cells. The activatable constructs were synthesized by esterification of a small molecule fluorophore with a fatty acid resulting in abl...

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Vydáno v:Bioconjug Chem
Hlavní autoři: Chiorazzo, Michael G., Bloch, Noah B., Popov, Anatoliy V., Delikatny, Edward J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862311/
https://ncbi.nlm.nih.gov/pubmed/26426140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00417
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