Nonprotecting Group Synthesis of a Phospholipase C Activatable Probe with an Azo-Free Quencher

[Image: see text] The near-infrared fluorescent activatable smart probe Pyro-phosphatidylethanolamine (PtdEtn)-QSY was synthesized and observed to selectively fluoresce in the presence of phosphatidylcholine-specific phospholipase C (PC-PLC). PC-PLC is an important biological target as it is known t...

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Publié dans:ACS Omega
Auteurs principaux: Liebov, Benjamin K., Arroyo, Alejandro D., Rubtsova, Natalia I., Osharovich, Sofya A., Delikatny, E. James, Popov, Anatoliy V.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2018
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026834/
https://ncbi.nlm.nih.gov/pubmed/29978148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00635
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