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Fluorophore-quencher based activatable targeted optical probes for detecting in vivo cancer metastases

In vivo molecularly targeted fluorescence imaging of tumors has been proposed as a strategy for improving cancer detection and management. Activatable fluorophores, which increased their fluorescence by 10-fold after binding tumor cells, result in much higher target to background ratios than convent...

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Main Authors: Ogawa, Mikako, Kosaka, Nobuyuki, Longmire, Michelle, Urano, Yasuteru, Choyke, Peter L., Kobayashi, Hisataka
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891627/
https://ncbi.nlm.nih.gov/pubmed/19718793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800115t
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