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H-type Dimer Formation of Fluorophores: A Mechanism for Activatable, in vivo Optical Molecular Imaging

In vivo molecular imaging with target-specific activatable “smart” probes, which only yield fluorescence at the intended target, enables sensitive and specific cancer detection because of high target to background ratios (TBR). Dimerization and fluorescence quenching has been shown to occur in conce...

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Bibliografiset tiedot
Päätekijät: Ogawa, Mikako, Kosaka, Nobuyuki, Choyke, Peter L, Kobayashi, Hisataka
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743556/
https://ncbi.nlm.nih.gov/pubmed/19480464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900089j
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