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H-type Dimer Formation of Fluorophores: A Mechanism for Activatable, in vivo Optical Molecular Imaging

In vivo molecular imaging with target-specific activatable “smart” probes, which only yield fluorescence at the intended target, enables sensitive and specific cancer detection because of high target to background ratios (TBR). Dimerization and fluorescence quenching has been shown to occur in conce...

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Dades bibliogràfiques
Autors principals: Ogawa, Mikako, Kosaka, Nobuyuki, Choyke, Peter L, Kobayashi, Hisataka
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743556/
https://ncbi.nlm.nih.gov/pubmed/19480464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900089j
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