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In vivo target-specific activatable near infrared optical labeling of humanized monoclonal antibodies
Imaging with labeled monoclonal antibodies may be useful in detecting, staging and monitoring tumors. Despite their high affinity and specificity, a critical limitation of antibody imaging is the high background signal due to prolonged clearance from the blood which reduces the tumor-to-background r...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790275/ https://ncbi.nlm.nih.gov/pubmed/19139133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0862 |
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