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A quantitative continuous enzyme assay of intramolecularly-quenched fluorogenic phospholipase substrates for molecular imaging

There has been recent growth in the development of activatable near-infrared (NIR) fluorescent probes for molecular imaging, generally designed by placing fluorochromes on a cleavable substrate in close proximity to one another, such that they self-quench, but fluoresce upon separation via enzymatic...

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Detalhes bibliográficos
Main Authors: Mawn, Theresa M., Popov, Anatoliy V., Delikatny, E. James
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528081/
https://ncbi.nlm.nih.gov/pubmed/22230285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.12.009
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