Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics

BACKGROUND: The emergence of antibiotic resistant pathogenic bacteria has reduced our ability to combat infectious diseases. At the same time the numbers of new antibiotics reaching the market have decreased. This situation has created an urgent need to discover novel antibiotic scaffolds. Recently,...

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Udgivet i:BMC Microbiol
Main Authors: Hoerr, Verena, Duggan, Gavin E., Zbytnuik, Lori, Poon, Karen K. H., Große, Christina, Neugebauer, Ute, Methling, Karen, Löffler, Bettina, Vogel, Hans J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862084/
https://ncbi.nlm.nih.gov/pubmed/27159970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0696-5
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