Characterization and prediction of the mechanism of action of antibiotics through NMR metabolomics

BACKGROUND: The emergence of antibiotic resistant pathogenic bacteria has reduced our ability to combat infectious diseases. At the same time the numbers of new antibiotics reaching the market have decreased. This situation has created an urgent need to discover novel antibiotic scaffolds. Recently,...

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Publicado en:BMC Microbiol
Autores principales: Hoerr, Verena, Duggan, Gavin E., Zbytnuik, Lori, Poon, Karen K. H., Große, Christina, Neugebauer, Ute, Methling, Karen, Löffler, Bettina, Vogel, Hans J.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862084/
https://ncbi.nlm.nih.gov/pubmed/27159970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0696-5
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