Endogenous and synthetic ABHD5 ligands regulate ABHD5-Perilipin interactions and lipolysis in fat and muscle

Fat and muscle lipolysis involves functional interactions of adipose triglyceride lipase (ATGL), α-β hydrolase domain-containing protein 5 (ABHD5), and tissue-specific perilipins 1 and 5 (PLIN1 and PLIN5). ABHD5 potently activates ATGL, but this lipase-promoting activity is suppressed when ABHD5 is...

詳細記述

保存先:
書誌詳細
出版年:Cell Metab
主要な著者: Sanders, Matthew A., Madoux, Franck, Mladenovic, Ljiljana, Zhang, Huamei, Ye, Xiangqun, Angrish, Michelle, Mottillo, Emilio P., Caruso, Joseph A., Halvorsen, Geoff, Roush, William R., Chase, Peter, Hodder, Peter, Granneman, James G.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862007/
https://ncbi.nlm.nih.gov/pubmed/26411340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.08.023
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