Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes

Current knowledge regarding acute regulation of adipocyte lipolysis is largely based on receptor-mediated activation or inhibition of pathways that influence intracellular levels of cAMP, thereby affecting protein kinase A (PKA) activity. We recently identified synthetic ligands of α-β-hydrolase dom...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pharmacol Exp Ther
Prif Awduron: Rondini, Elizabeth A., Mladenovic-Lucas, Ljiljana, Roush, William R., Halvorsen, Geoff T., Green, Alex E., Granneman, James G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2017
Pynciau:
Drug Discovery and Translational Medicine
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698943/
https://ncbi.nlm.nih.gov/pubmed/28928121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.243253
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