Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes

Cardiac myosin binding protein-C (cMyBP-C) is a structural and regulatory component of cardiac thick filaments. It is observed in electron micrographs as seven to nine transverse stripes in the central portion of each half of the A band. Its C-terminus binds tightly to the myosin rod and contributes...

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Pubblicato in:J Mol Cell Cardiol
Autori principali: McNamara, James W., Li, Amy, Smith, Nicola J., Lal, Sean, Graham, Robert M., Kooiker, Kristina Bezold, van Dijk, Sabine J., dos Remedios, Cristobal G., Harris, Samantha P., Cooke, Roger
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861668/
https://ncbi.nlm.nih.gov/pubmed/27021517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.03.009
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