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Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs
Age-associated decline in organ function governs life span. We determined the effect of aging on lung function and cellular/molecular changes of 8- to 32-month old mice. Proteomic analysis of lung matrix indicated significant compositional changes with advanced age consistent with a profibrotic envi...
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| Pubblicato in: | J Gerontol A Biol Sci Med Sci |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861645/ https://ncbi.nlm.nih.gov/pubmed/25568097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu241 |
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