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Cellular senescence increases expression of bacterial ligands in the lungs and is positively correlated with increased susceptibility to pneumococcal pneumonia

Cellular senescence is an age-associated phenomenon that promotes tumor invasiveness due to the secretion of pro-inflammatory cytokines, proteases, and growth factors. Herein we demonstrate that cellular senescence also potentially increases susceptibility to bacterial pneumonia caused by Streptococ...

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Detalhes bibliográficos
Main Authors: Shivshankar, Pooja, Boyd, Angela Rodriguez, Le Saux, Claude Jourdan, Yeh, I-Tien, Orihuela, Carlos J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173515/
https://ncbi.nlm.nih.gov/pubmed/21615674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00720.x
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