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Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells

During G(1)-phase of the cell cycle, normal cells respond first to growth factors that indicate that it is appropriate to divide and then later in G(1) to the presence of nutrients that indicate sufficient raw material to generate two daughter cells. Dividing cells rely on the “conditionally essenti...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Patel, Deven, Menon, Deepak, Bernfeld, Elyssa, Mroz, Victoria, Kalan, Sampada, Loayza, Diego, Foster, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861495/
https://ncbi.nlm.nih.gov/pubmed/26921316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710145
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