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Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells

During G(1)-phase of the cell cycle, normal cells respond first to growth factors that indicate that it is appropriate to divide and then later in G(1) to the presence of nutrients that indicate sufficient raw material to generate two daughter cells. Dividing cells rely on the “conditionally essenti...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Patel, Deven, Menon, Deepak, Bernfeld, Elyssa, Mroz, Victoria, Kalan, Sampada, Loayza, Diego, Foster, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861495/
https://ncbi.nlm.nih.gov/pubmed/26921316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710145
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