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Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
SMYD3 is a SET domain-containing N-lysine methyltransferase associated with multiple cancers. Its reported substrates include histones (H3K4 and H4K5), vascular endothelial growth factor receptor 1 (VEGFR1 Lys(831)) and MAP3 kinase kinase (MAP3K2 Lys(260)). To reveal the structural basis for substra...
Shranjeno v:
izdano v: | J Biol Chem |
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Main Authors: | , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Biochemistry and Molecular Biology
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4861483/ https://ncbi.nlm.nih.gov/pubmed/26929412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709832 |
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