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Exploration of the Substrate Preference of Lysine Methyltransferase SMYD3 by Molecular Dynamics Simulations
[Image: see text] SMYD3, a SET and MYND domain containing lysine methyltransferase, catalyzes the transfer of the methyl group from a methyl donor onto the Nε group of a lysine residue in the substrate protein. Methylation of MAP3 kinase kinase (MAP3K2) by SMYD3 has been implicated in Ras-driven tum...
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| Опубликовано в: : | ACS Omega |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2019
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881823/ https://ncbi.nlm.nih.gov/pubmed/31788587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01842 |
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