An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein

Most proinflammatory actions of C-reactive protein (CRP) are only expressed following dissociation of its native pentameric assembly into monomeric form (mCRP). However, little is known about what underlies the greatly enhanced activities of mCRP. Here we show that a single sequence motif, i.e. chol...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Li, Hai-Yun, Wang, Jing, Meng, Fan, Jia, Zhe-Kun, Su, Yang, Bai, Qi-Feng, Lv, Ling-Ling, Ma, Fu-Rong, Potempa, Lawrence A., Yan, Yong-Bin, Ji, Shang-Rong, Wu, Yi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2016
נושאים:
Molecular Bases of Disease
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861447/
https://ncbi.nlm.nih.gov/pubmed/26907682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695023
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