An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein

Most proinflammatory actions of C-reactive protein (CRP) are only expressed following dissociation of its native pentameric assembly into monomeric form (mCRP). However, little is known about what underlies the greatly enhanced activities of mCRP. Here we show that a single sequence motif, i.e. chol...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Hai-Yun, Wang, Jing, Meng, Fan, Jia, Zhe-Kun, Su, Yang, Bai, Qi-Feng, Lv, Ling-Ling, Ma, Fu-Rong, Potempa, Lawrence A., Yan, Yong-Bin, Ji, Shang-Rong, Wu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861447/
https://ncbi.nlm.nih.gov/pubmed/26907682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695023
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