An Intrinsically Disordered Motif Mediates Diverse Actions of Monomeric C-reactive Protein

Most proinflammatory actions of C-reactive protein (CRP) are only expressed following dissociation of its native pentameric assembly into monomeric form (mCRP). However, little is known about what underlies the greatly enhanced activities of mCRP. Here we show that a single sequence motif, i.e. chol...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Li, Hai-Yun, Wang, Jing, Meng, Fan, Jia, Zhe-Kun, Su, Yang, Bai, Qi-Feng, Lv, Ling-Ling, Ma, Fu-Rong, Potempa, Lawrence A., Yan, Yong-Bin, Ji, Shang-Rong, Wu, Yi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861447/
https://ncbi.nlm.nih.gov/pubmed/26907682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695023
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