Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7)

Mutations in TSC1 or TSC2 cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by the occurrence of benign tumors in various vital organs and tissues. TSC1 and TSC2, the TSC1 and TSC2 gene products, form the TSC protein complex that senses specific cellular growth con...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Qin, Jiayue, Wang, Zhizhi, Hoogeveen-Westerveld, Marianne, Shen, Guobo, Gong, Weimin, Nellist, Mark, Xu, Wenqing
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861430/
https://ncbi.nlm.nih.gov/pubmed/26893383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.701870
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