The TSC1-TSC2 complex consists of multiple TSC1 and TSC2 subunits

BACKGROUND: Mutations to the TSC1 and TSC2 genes cause the disease tuberous sclerosis complex. The TSC1 and TSC2 gene products form a protein complex that integrates multiple metabolic signals to regulate the activity of the target of rapamycin (TOR) complex 1 (TORC1) and thereby control cell growth...

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Bibliographic Details
Main Authors: Hoogeveen-Westerveld, Marianne, van Unen, Leontine, van den Ouweland, Ans, Halley, Dicky, Hoogeveen, Andre, Nellist, Mark
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517901/
https://ncbi.nlm.nih.gov/pubmed/23006675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-13-18
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