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The TSC1-TSC2 complex consists of multiple TSC1 and TSC2 subunits
BACKGROUND: Mutations to the TSC1 and TSC2 genes cause the disease tuberous sclerosis complex. The TSC1 and TSC2 gene products form a protein complex that integrates multiple metabolic signals to regulate the activity of the target of rapamycin (TOR) complex 1 (TORC1) and thereby control cell growth...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517901/ https://ncbi.nlm.nih.gov/pubmed/23006675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-13-18 |
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