Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7)

Mutations in TSC1 or TSC2 cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by the occurrence of benign tumors in various vital organs and tissues. TSC1 and TSC2, the TSC1 and TSC2 gene products, form the TSC protein complex that senses specific cellular growth con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Qin, Jiayue, Wang, Zhizhi, Hoogeveen-Westerveld, Marianne, Shen, Guobo, Gong, Weimin, Nellist, Mark, Xu, Wenqing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861430/
https://ncbi.nlm.nih.gov/pubmed/26893383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.701870
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