P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes

Type 1 diabetes (T1D) causes a range of skeletal problems, including reduced bone density and increased risk for bone fractures. However, mechanisms underlying skeletal complications in diabetes are still not well understood. We hypothesize that high glucose levels in T1D alters expression and funct...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Seref-Ferlengez, Zeynep, Maung, Stephanie, Schaffler, Mitchell B., Spray, David C., Suadicani, Sylvia O., Thi, Mia M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861344/
https://ncbi.nlm.nih.gov/pubmed/27159053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155107
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